摘要
目的 分析肝细胞肝癌的临床特 征,评估MRI各序列扫描肝细胞肝癌的图 像特点及诊断价值。方法 回顾性分析我 院自2013年4月-2015年4月收治的46例肝 细胞肝癌患者的临床资料,所有患者入院 后均接受MRI三期扫描与检查,且影像学 资料完整,总结肝细胞肝癌临床特点及 MRI在其临床诊断中的应用价值。结果 46 例肝细胞肝癌患者共计50个病灶,其中高 分化23个,中分化13个,低分化14个;位 于肝右叶30个,肝左叶20个;T1WI序列扫 描可见稍低信号36个,等信号8个,稍高 信号6个;T2WI序列呈稍高信号44个,其 中4个病灶中央可见更高信号,6个病灶呈 等信号;DWI序列呈高信号30个,略高信 号15个,等信号5个。结论 MRI各序列扫 描对肝细胞肝癌病灶大小、内部结构、边 缘、血供显示均有其优势,对肝细胞肝癌 组织分化程度的确立有其重要的价值,同 时可全面显示患者病灶强化特点与微形态 特征,为其治疗与预后评估提供参考。
Objective To analyze the clinical features of hepatocellular carcinoma and to evaluate the characteristics of images and diagnostic value of MRI sequence scanning in hepatocellular carcinoma. Methods The clinical data of 46 patients with hepatocellular carcinoma treated in our hospital from April 2013 to April 2015 were analyzed retrospectively. After admission, all patients underwent MRI three phase scan and examination and the imaging data were complete. The clinical features of hepatocellular carcinoma and the application value of MRI in clinical diagnosis were summarized. Results There were 50 lesions in 46 patients with hepatocellular carcinoma, including 23 highly differentiated lesions, 13 moderately differentiated lesions and 14 poorly differentiated lesions; 30 lesions were located in the right lobe of liver and 20 in the left lobe of the liver; T1WI sequence scan showed 36 slightly lower signal, 8 equal signal and 6 slightly higher signal; T2WI sequence showed 44 slightly higher signal, including 4 of the lesions showed higher signal and 6 lesions showed equal signal; DWI sequence showed 30 higher signal, 15 slightly higher signal and 5 equal signal. Conclusion MRI sequence scan has its own advantages in showing the size, internal structure, edge and blood supply of hepatocellular carcinoma lesions. It is of important value in determination of the differentiation degree of hepatocellular carcinoma tissues. It can also show the characteristics of lesion enhancement and micro-morphological characteristics and provide reference for the treatment and prognosis.
【关键词】肝细胞肝癌;MRI;诊断;临床特点
【中图分类号】R735.7
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.01.025
前言
肝细胞肝癌为肝脏常见恶性肿瘤,发病率、致死率高。早期发现 及准确定性病灶的性质,确定其范围、数量是肝细胞肝癌诊断的重要 基础。磁共振成像有其组织分辨率高,信号特点佳的优势,在肝细胞 肝癌中诊断价值较为肯定[1,2]。而磁共振扩散加权成像归于磁共振功 能成像的范畴,其不仅可反映肝细胞肝癌的病变形态学,同时可评估 患者病变的组织结构情况及癌症分化程度,并作为患者预后评定的依 据[3]。
中国CT和MRI杂志
第14卷, 第 1 期
2016年01月
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