目的探讨MRI在非乙醇中毒性 Wernicke脑病诊断中的应用价值。方法 回顾性分析经临床治疗确诊的3例非乙醇 中毒性Wernicke脑病患者的影像资料， 并结合文献复习。结果 3例患者MR表现 为III、IV脑室旁及双侧丘脑内侧、中 脑顶盖区及中脑导水管周围对称性异常 信号，T1加权像呈低信号，T2加权像呈 高信号，T2 Flair成像及弥散加权成像 (DWI)呈高信号。结论 Wernicke脑病的 分布具有特征性，MRI表现具有特异性， 对其早期诊断具有较高价值。

Objective To investigate the value of MRI in the diagnosis of non-alcoholic Wernicke encephalopathy. Methods The imaging date of 3 patients with clinically proved non-alcoholic Wernicke encephalopathy were retrospectively analyzed and reviewed combined with literature. Results 3 patients showed symmetric low signal intensity in T1WI, high signal intensity in T2WI, T2 Flair and DWI in the regions surrounding III and IV ventricles, inside of bilateral thalamus, tectum of midbrain and regions surrounding midbrain aqueduct. Conclusions Lesion distribution of Wernicke encephylopathy has its characteristics. MRI manifestations of Wernicke encephylopathy have certain specificity and high value in the early diagnosis of this disease