目的探讨腰椎内固定术后T2- mapping成像定量评估邻近节段椎间盘退 变的可行性和可重复性。方法 24例患者 于腰椎内固定术前1周内及术后6-8周分 别行腰椎MR T2-mapping成像检查，并测 量邻近节段椎间盘髓核的T2值。比较同一 观察者不同时间和不同观察者之间测量结 果的可重复性。结果 24例患者均成功测 量邻近节段椎间盘髓核的T2值。内固定近 侧邻近椎间盘髓核术前和术后的T2值分别 为93.2±22.3ms和95.5±20.1ms，差异无 统计学意义(t=-1.00，P＞0.05)。远侧邻 近椎间盘髓核术前和术后的T2值分别为 87.9±27.7ms和83.7±23.0ms，差异无统 计学意义(t=1.77，P＞0.05)。同一观察 者或不同观察者间的组内相关系数(ICC) 为0.85-0.94(P＜0.01)。结论 腰椎内固 定术后T2-mapping成像测量T2值是可行 的，且可重复性高，有助于定量评估邻近 节段椎间盘的退变情况。

Objective To explore the feasibility and reproducibility of MR T2- mapping technique in evaluating intervertebral disk degeneration of adjacent segment after internal fixation surgery. Methods Within 1 week preoperatively and 6 to 8 weeks postoperatively,24 patients were underwent T2-mapping examination. The T2 value of nucleus pulposus was measured by two senior MRI radiologists. To assess the reproducibility of this evaluation, inter-and intra-observer statistics were performed. Results The T2 values of 24 patients were measured successfully. The preand postoperative T2 values of the adjacent proximate disks were 93.2±22.3ms and 95.5±20.1ms respectively (t=-1.00,P＞0.05),and the pre- and postoperative T2 values of the adjacent distal disks were 87.9±27.7ms and 83.7±23.0ms(t=1.77,P＞0.05). The inter- and intra-observer analysis yielded intraclass correlation coefficients (ICC) for measures in a range from 0.85 to 0.94(P＜0.01). Conclusion MR T2-mapping examination after internal fixation surgery is feasible, it will be a potential quantitative method in evaluating intervertebral disk degeneration of adjacent segment for its excellent reproducibility.