目的探讨膝关节相控阵线圈在 新生儿脑部MRI检查中扫描参数优化选 择。方法 应用膝关节相控阵线圈对足月 新生儿行脑部扫描，分别采用传统脑部扫 描参数和优化后扫描参数，获取横断位T1 加权、T2加权、T2 FLAIR、扩散加权成像 及矢状位T1加权成像等图像，比较两组图 像质量、图像信噪比和满足影像诊断率。 结果 用膝关节相控阵线圈顺利完成45例 足月新生儿行脑部扫描，其中用传统脑部 扫描参数22例，用优化后扫描参数23例， 两组扫描参数所得图像信噪比经两独立样 本t检验，两组比较差别无统计学意义(P ＞0.05)。两组扫描参数所得图像满足影 像诊断率经四格表χ2 检验，两组比较差 别无统计学意义(P＞0.05)；优化组扫描 时间较之传统组减少1/3。结论 优化组扫 描参数能代替传统脑部扫描参数，优化组 扫描时间及SAR值均可减少。优化组扫描 参数更适合膝关节相控阵线圈新生儿脑部 MRI检查。

Objective To investigate the optimization of neonatal brain MR imaging with knee phased-array coil. Methods Forty-five newborns participated in the study and were scanned with a knee phased-array coil. Imaging techniques, including T1- weighted imaging, T2-weighted imaging, T2 FLAIR imaging, and diffusion weighted imaging at the axial orientation, and T1-weighted imaging at the sagittal orientation, were respectively conducted. Twenty newborns were scanned with the conventional imaging parameters, and the other twenty-three were scanned with the optimized imaging parameters. Signal-to noise ratio (SNR) and image quality for clinical diagnosis were compared between paired scans. Results All data was successfully acquired. No statistically significant difference of SNR was observed between the conventional and the optimized imaging parameters (P-value > 0.05). In addition, a Chi-square test suggested no significant difference of image quality for clinical diagnosis between the two sets of imaging parameters (P-value > 0.05). The time scanned with the optimized imaging parameters was less than that scanned with the conventional imaging parameters. Conclusion With the advantages of halving scan time and specific absorption rate, the optimized neonatal brain MR imaging parameters were superior to the conventional ones, and were more suitable for neonatal brain MR examination with knee phased-array coil.