摘要
目的探讨18F-FDG PET/CT显像在 判断乳腺癌患者术后复发和病灶转移中的 应用价值。方法 选取医院收治的疑似乳 腺癌术后复发或病灶转移患者79例作为研 究对象,原发病灶经手术病理证实为乳腺 癌患,均行18F-FDG PET/CT显像检查,并 与病理随访对比。结果 以病理随访结果 作为“金标准”,18F-FDG PET/CT检查显 示术后复发或病灶转移准确性、特异性、 敏感性分别为94.94%、94.62%、95.65%; 检测淋巴结转移的准率性、敏感性、特异 性分别为91.52%、97.46%、79.48%,与病 理随访诊断的一致性较高。结论 18F-FDG PET/CT显像在诊断乳腺癌患者术后复发或 病灶转移中具有较高的应用价值。
Objective To investigate the application value of 18F-FDG PET/CT imaging in the judgement of recurrence or metastatic lesions in patients with breast cancer after surgery. Methods 79 cases of patients with suspected recurrence or metastatic lesions after breast cancer surgery in the hospital were selected as the research objects. Patients with breast cancer of which the primary lesions were confirmed by surgery and pathology all underwent 18F-FDG PET/CT imaging examination which were compared with pathologic follow-up. Results Taking the results of pathological follow-up as the gold standard, the accuracy, specificity and sensitivity of 18F-FDG PET / CT in detection of recurrence or metastatic lesions were 94.94%, 94.62% and 95.65% while in the detection of lymph node metastasis were 91.52%, 97.46% and 79.48%, the consistency of which with pathological follow-up diagnosis was high. Conclusion 18F-FDG PET/CT imaging is of high value in the diagnosis of recurrence or metastasis of breast cancer.
【关键词】乳腺癌;18F-FDG PET/CT显像; 术后复发;转移;准确性
【中图分类号】R445.6;R737.9
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.11.014
前言
乳腺癌是女性患者常见的恶性肿瘤之一,致死率较高。据不完全 统计,高达35%左右乳腺癌患者术后会出现局部复发或转移,需定期行 超声、CT等影像学检查,了解疾病复发情况,及时予以干预治疗,延 长中位生存周期[1]。然而,超声、CT、胸片等影像学方式在诊断乳腺 癌复发和转移中存在一定局限性,难以全面评估疾病发展情况。18FFDG PET/CT显像以代谢为基础,在临床诊断乳腺癌复发和转移中具有 明显优势。对此,本文分析了18F-FDG PET/CT显像对乳腺癌复发和病灶 转移的诊断情况,并与病理随访结果对比,以探讨其临床应用价值, 现报道如下。
中国CT和MRI杂志
第13卷, 第 11 期
2015年11月
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