摘要
目的分析螺旋CT低剂量胃充气 造影扫描在胃癌诊断中的效果。方法 90 例经胃镜检查拟诊胃癌并需要做螺旋CT 检查患者,按就诊顺序随机分成3组,每 组30例。A组参照组采用固定毫安法, 120kv,150mAs;B、C组低剂量组均采用智 能毫安调制法,管电压120KV,使用智能 毫安法,噪声指数SD值分别为12、15,造 影剂均使用碘海醇(300mgI/ml),1.2ml/ kg,扫描后将原始薄层图像在东芝16排CT Vitrea工作站上进行后处理,将轴位图像 和重组图像传送至NFPACS上,分别记录每 组病例的CT容积剂量指数(CTDIvol),评 价图像质量。结果 A、B扫描图像质量的 差异不具有统计学意义(P>0.05),A、B 组剂量加权指数降低率的差异具有统计学 意义,A、C组间扫描图像质量、剂量加 权指数降低率的差异具有统计学意义(P <0.05),B、C组间扫描图像质量/剂量加 权指数降低率的差异具有统计学意义。结 论 B、C组使用智能毫安调制法可以有效 降低辐射剂量值,B组扫描条件可以作为 常规扫描方案,以降低辐射剂量;C组图 像质量显示欠佳,容易造成漏诊,该方案 不推荐应用于胃部肿瘤扫描;在不影响诊 断准确性的前提下,在一定范围内减少辐 射剂量可获得与常规剂量相同的影像信息 和图像质量,应该在临床中进行推广和应 用,更好的对胃癌进行诊断,力求减低病 人的辐射量,提高低剂量筛查早期胃癌的 诊断率。
Objective to analyze the value on the low-dose spiral CT scan of inflated stomach in the diagnosis of gastric cancer. Methods 90 cases of stomach cancer diagnosed by endoscopy who need to do spiral CT san examination were divided into three groups averagely in order. A group, the reference group was taking the way of a fixed tube mA, 120 KV, 150 mAs; B,C Group,as the low-dose group were taking the smart mA modulation method, the tube voltage of 120 KV, using smart mA law, the noise index values were SD 12 15, contrast agents are using iohexol (300 mgI/ml) 1.2 ml/kg. After scanning the original image on a thin layer were transferred into Toshiba 16-slice CT Vitrea workstation to do the postprocessing, and then the axial and reconstructive images were sended into NFPACS,the volume CT dose index (CTDIvol) were recorded in cases of each group, finally to evaluate the image quality. Results A, B-scan image quality difference was not statistically significant (P>0.05), the difference of A and B dose weighted index was statistically significant, the image quality between A and C, and their dose-weighted index decreased rate were statistically significant (P<0.05). The image quality and dose-weighted index decreased rate was statistically significant. Conclusions B, C using smart mA modulation can effectively reduce the radiation dose values, and group B scanning conditions can be a conventional scanning program to reduce radiation dose; Group C showed poor image quality, easily lead to misdiagnosis, the program is not recommended in the stomach tumor scans; Without affecting the diagnostic accuracy of the premise, within a certain range to reduce the radiation dose can be obtained the same image information and image quality as the conventional dose, which should be the promoted to apply in clinical practice, it is better for stomach cancer diagnosis and that means it can help to increase the diagnostic rate of low-dose screening.
【关键词】螺旋CT扫描;低剂量;胃癌诊断;图像质量;剂量加权指数
【中图分类号】R735.2;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.05.027
前言
胃癌是我国最常见的恶性肿瘤之一,在我国其发病率居各类肿瘤 的首位,每年约有17万人死于胃癌,几乎接近全部恶性肿瘤死亡人数 的1/4,且每年还有2万以上新的胃癌病人产生出来,胃癌确实是一 种严重威胁人民身体健康的疾病[1-2]。胃癌可发生于任何年龄,但以 40~60岁多见,男多于女,约为2:1。胃癌可发生于胃的任何部位, 但多见于胃窦部,尤其是胃小弯侧。根据癌组织浸润深度分为早期胃 癌和进展期胃癌中、晚期胃癌。胃癌早期症状常不明显,如捉摸不定 的上腹部不适、隐痛、嗳气、泛酸、食欲减退、轻度贫血等,部分类 似胃十二指肠溃疡或慢性胃炎症状[3]。后期常有癌肿转移,出现腹部 肿块、左锁骨上淋巴结肿大、黑便、腹水及严重营养不良等。目前准 要的诊断手段有X线钡餐检查、纤维胃镜检查、腹部超声、螺旋CT与正 电子发射成像检查等,均有一定的优缺点.本研究螺旋CT低剂量胃充气 造影扫描在胃癌的扫描方案,为广大临床工作者提供参考依据,帮助 临床拓宽对胃癌的有效检查方法,并在早期胃癌的低剂量筛查中提供 必要的帮助。
中国CT和MRI杂志
第13卷, 第 5 期
2015年05月
相关文章