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小肝细胞癌的少见CT强化表现及分析

作者:廖雪燕 谢鉴津 邱菊生 邱清香  许凯华  任碧连

所属单位:福建医科大学附属龙岩市第一医院放射科(福建 龙岩 364000)

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摘要

目的研究小肝细胞癌的少见 CT强化表现及原因,以提高小肝细胞癌 的诊断准确性。方法 回顾性分析经手 术及病理证实的20例小肝细胞癌的25个 癌灶的少见CT强化表现,与典型肝细胞 癌强化图像对比,总结其影像学特征。 结果 20例患者共发现25个癌灶。除2例 患者平扫呈等密度影,其它病灶平扫均 呈低密度灶。增强后5例动脉期呈高密 度影,门脉期、平衡期等密度影;2例 动脉期、门脉期呈高密度影,平衡期呈 低密度影;3例动脉期、门脉期呈高密 度影,平衡期仍呈高密度影,边缘见环 形廓清现象;2例增强后动脉期呈等密 度影,门脉期、平衡期呈低密度影,边 界较清楚;2例增强后三期未见明显强 化,即“三低”病灶;3例增强后动脉 期呈轻度强化,强化程度低于肝实质, 边界较清楚并呈轻度不规整,门脉期仍 呈低密度影,病灶内散在更低密度灶, 较前明显,平衡期呈低密度影;3个患 者呈多灶性起源,其中2例患者各3个 病灶,各病灶呈现同步强化;1例患者 2个病灶,呈不同步强化。结论 小肝细 胞癌的少见强化表现多种多样,但三期 动态CT扫描技术是小肝细胞癌诊断的可 靠影像学诊断方法。

Objective To investigate the rare CT enhancement performances of small hepatocellular carcinoma and the reasons. To improve the diagnostic accuracy of small hepatocellular carcinoma(SHCC). Methods The rare CT enhancement performances of 20 patients with SHCC(25 lesions) confirmed by operation and pathology were retrospectively analyzed and were compared with the enhancement performances of typical SHCC. The imaging characteristics were summarized. Results 25 lesions were found in 20 cases. Except 2 lesions showed isodense focuses, the other 23 lesions showed high density focuses in plain CT scan. On contrast- enhanced CT imges, 5 cases showed high density focuses in arterial phase and isodense in portal vein and equilibrium phase. 2 cases showed high density focuses in arterial and portal venous phase and low density focuses in equilibrium phase. 3 cases showed high density focuses in arterial and portal venous phase and edge annular clearance in equilibrium phase. 2 cases showed isodense focuses in arterial phase and low density focuses in portal venous and equilibrium phase.2 cases showed no enhancement in three phase("three low density" lesions). 3 cases showed mild enhancement in arterial phase(less than the liver) with the clear and slight irregular boundary, and it showed low density focuses in the portal venous phase with scattered lower density focuses and low density focuses in equilibrium period. 3 cases were multiple focal original, of which 2 cases had 3 lesions respectively and the lesions showed synchronous enhancement, and 2 lesions in 1 case showed asynchronous enhancement. Conclusion There are various rare CT enhancement performances of small hepatocellular carcinoma. Three phase dynamic CT scan is a reliable diagnostic method in the diagnosis of small hepatic cell cancer.

【关键词】小肝细胞癌;CT;影像学表现

【中图分类号】R735.7

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.04.18

前言

小肝细胞癌是目前临床上最常见的恶性肿瘤之一,而螺旋CT双期 或三期增强扫描已越来越广泛地应用于临床,在诊断小肝细胞癌中正 发挥着越来越重要的作用,已成为首选的检查方法[1-2]。绝大多数小肝 细胞癌的典型CT表现(见图1-4)为平扫呈低密度影,增强后动脉期呈高 密度,其密度高于正常肝组织,但低于同层主动脉,门脉期强化密度 迅速下降,低于肝组织,呈“快进快出”的特点[3]。根据其典型CT表 现诊断不难,但有10%患者CT表现不典型给诊断带来一定困难[4]。笔者 拟对这种少见CT强化表现进行深入研究,以提高对本病的认识。