摘要
目的探讨采用股骨头髓芯减压 加碳酸钙人工骨植入术治疗股骨头缺血性 坏死的疗效。方法 2010年5月至2013年6 月,采用股骨头髓芯减压加植骨术治疗 FicatⅠ-Ⅲ期股骨头缺血性坏死患者42 例;年龄27-57岁。术前疼痛时间6-18个 月,平均10个月。所有患者于术前、术后 3个月和6个月行Harris评分,并进行双髋 关节X线片及CT检查。结果 所有病人随访 6-36个月,平均18个月。Harris评分术后 3个月、术后6个月均较术前显著上升,且 术后6个月显著高于术后3个月,P<0.01。 术后3个月及术后6个月的临床疗效较术 前显著改善,P<0.01;且术后6个月的临 床疗效显著优于术后3个月,P<0.05。术 后3个月及术后6个月患者的影像学稳定 率较术前显著改善,P<0.01;且术后6个 月的影像学稳定率显著优于术后3个月, P<0.05。术后6个月,37例病人X线片显示 髋关节保持基本生理形态,无明显坏死进 展,CT显示坏死区不同程度修复,3例单 髋症状加重,1例术后3月显示股骨头坏死 加重,选择手术,1例因外伤后造成骨股 颈骨折后选择手术治疗。结论 股骨头髓 芯减压加硫酸钙人工骨植入术治疗股骨头 缺血性坏死具有手术损伤小,关节功能恢 复快,临床症状明显减轻,短期效果满意 的优点,长期疗效值得期待。
Objective To explore the use of femoral medullary core decompression with calcium carbonate artificial bone implantation for the treatment of ischemic necrosis of femoral head. Methods In May 2010 to June 2013, the thigh bone marrow core decompression for the treatment of bone graft Ficat Ⅰ - Ⅲ options were 42 patients with ischemic necrosis of bone;Age 27-57,preoperative pain 6 to 18 months, an average of 10 months. All of the patients in the preoperative and postoperative 3 months and 6 months Harris score, and dual hip X-ray and CT examination. Results All patients were followed up for 6 to 36 months, an average of 18 months. Harris score at 3 months, 6 months after operation compared with preoperative rise sharply(P<0.01).After 3 months and 6 months the clinical curative effect of preoperative significantly improved, P<0.01; And the clinical curative effect of postoperative 6 months was superior to that of postoperative 3 months, P<0.05. Patients with postoperative 3 months and 6 months after the imaging stability factor of the preoperative improved significantly, P<0.01; And 6 months after imaging stability factor significantly better than 3 months postoperatively, P<0.05.6 months postoperatively, 37 cases of patients with X-ray shows hip keep basic form, no obvious necrosis, CT showed necrosis area, different degree of repair, 3 cases of single hip symptoms worsen, 1 case of postoperative march showed femoral head necrosis is aggravating, choose operation, 1 case of femoral neck fracture caused by trauma after bone choice after surgery. Conclusions Marrow core decompression plus calcium sulphate artificial femoral head bone implantation treatment of ischemic necrosis of femoral head with a small surgical injury, quicker recovery of joint function, relieve clinical symptoms, the advantages of the short-term effect is satisfied, curative effect is worth looking forward to for a long time.
【关键词】股骨头坏死;髓芯减压手术; 人工骨植入
【中图分类号】R681.8
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2015.03.29
前言
股骨头坏死(Osteonecrosis of the femoral head,ONFH),多 发于20~40岁的青壮年,具有严重的破坏性,病程较长,致残率高。 其病因较多,最终导致股骨头缺血、坏死,发生退行性病变,影响患 者的生活质量。目前外科治疗主要针对疾病终末期骨质变化采取相应 处理,包括髓芯减压术、骨移植术、截骨术、干细胞移植术、全髋关 节置换术(TRA)和表面髋关节置换术(HRA)等[1]。虽然临床上对于早期 ONFH患者常实行单纯髓芯减压术,但对于Ficat II期以上的患者, 疗效并不满意[2]。髓芯减压术结合人工骨植入,可以满足力学支撑 强度,对于股骨头产生即刻支撑作用,避免股骨头继续塌陷[3]。我科 2010年5月至2013年6月采用髓芯减压加碳酸钙人工骨植入术治疗股骨 头缺血性坏死42例,疗效显著,现报道如下。
中国CT和MRI杂志
第13卷, 第 3 期
2015年03月
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