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磁共振弥散张量成像诊断轻度脊髓型颈椎病的价值

作者:黄 波 刘 彪 黄伟兰 莫旭林 覃若萍

所属单位:广西贵港市人民医院放射科(广西 贵港 537100)

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摘要

目的探讨核磁共振弥散张量 成像诊断轻度脊髓型颈椎病的临床价 值。方法 入选我院2012年6月至2014年 6月收治的轻度脊髓型颈椎病患者62例 (按照颈髓磁共振平扫结果分为A组和 B组:A组32例,颈髓信号正常,颈髓 60个节段受压;B组30例,颈髓信号正 常,硬膜囊63个节段受压),同时入选 30例体检健康者(C组)进行90个颈髓节 段磁共振检查,评估各组的分数各向 异性值(FA)及表观扩散系数(ADC),评 估平行于颈椎的长径、前后径、左右径 的本征值E1、E2、E3,计算出平均弥散 系数MD值、横向平均弥散系数E⊥值: MD=(E1+E2+E3)/3;E⊥=(E2+E3)/2。结 果 健康对照组不同脊髓节段FA值及ADC 值之间差异无统计学意义(P>0.05);A组 的脊髓节段平均ADC值显著高于C组,差 异具有统计学意义(P<0.05);A组的脊髓 节段FA平均值显著低于C组,差异具有统 计学意义(P<0.05);B组的脊髓节段平 均ADC值显著高于C组,差异具有统计学 意义(P<0.05);B组的脊髓节段FA平均 值显著低于C组,差异具有统计学意义 (P<0.05);两组的E1值比较差异无统计学 意义(P>0.05),病变组的E2、E3、MD值、 E⊥值指标显著低于健康组,差异具有统 计学意义(P<0.05)。结论 轻度脊髓型颈 椎病进行磁共振张量成像检查,可准确早 期量化该病的颈髓微结构变化,对早期诊 断发现轻度脊髓型颈椎病诊断具有重要的 临床意义。

Objective to investigate the magnetic resonance diffusion tensor imaging in the diagnosis of mild myelopathic type. Methods in our hospital in 2012.6-2014.6 were 62 cases of mild spondylotic myelopathy (according to the cervical spinal mri scan results are divided into group A and group B, group A 32 cases, normal cervical spinal signal, compression of cervical spinal 60 segment; group B, 30 cases (group C)normal cervical spinal signal, compression of dural sac 63 section), and 30 healthy subjects were selected 90 cervical spinal segment mri examination, evaluation of each value fractional anisotropy (FA) and apparent diffusion coefficient (ADC).Evaluation parallel to the length to diameter of the cervical spine, before and after about diameter, the diameter of the eigenvalue E1, E2 and E3, calculate the average dispersion coefficient value, average transverse dispersion coefficient E⊥ an MD, MD=(E1+E2+E3)/3; E⊥=coming (E2 and E3)/2. Results healthy controls different spinal cord segment between the FA and ADC values differences had no statistical significance (P>0.05); Spinal cord segmental average ADC values of group A is significantly higher than in group C, statistically significant difference (P<0.05); Group A spinal cord segmental FA average significantly lower than that of group C, statistically significant difference (P<0.05); Group B of the spinal cord segmental average ADC values significantly higher than that of group C, statistically significant difference (P<0.05); Group B of the spinal cord segmental FA average significantly lower than that of group C, statistically significant difference (P<0.05). Conclusion mild magnetic resonance tensor imaging myelopathic type cervical vertebra disease, can accurately quantify the cervical spinal microstructure changes of the disease, early mild myelopathic type cervical vertebra disease diagnosis of early diagnosis findings have important clinical significance.

【关键词】表观扩散系数;分数各向异性值;弥散张量成像技术

【中图分类号】R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672-5131.2015.03.06

前言

脊髓型颈椎病是由于颈椎椎体退化及相邻软组织(如椎间盘突出、 椎体后缘骨刺、后纵韧带骨化、黄韧带肥厚或钙化、椎管狭窄等)的 退变造成了对脊髓的直接压迫,加上剧烈的运动或长期的不良姿势等 动态因素的影响,导致脊髓受压或脊髓缺血,继而出现脊髓的功能障 碍,临床表现如四肢麻木无力、活动不灵、走路时有踩棉花的感觉 等,而轻度脊髓型颈椎病早期无特异性症状,临床极易漏诊[1]。有研 究认为,轻度脊髓型颈椎病进行磁共振弥散张量成像诊断,诊断率高 [2]。探析轻度脊髓型颈椎病的最佳诊断方案具有重要的临床意义,故 我院2012年6月至2014年6月轻度脊髓型颈椎病患者进行磁共振弥散张 量成像检查,效果满意,现报道如下。