Objective To investigate the value of dual source CT perfusion imaging in the quantitative study of cerebral hemodynamics in normal population and to measure the normal range of perfusion parameters. Methods A total of 30 healthy volunteers with no craniocerebral disease were collected and the CT perfusion scan was performed. The CBV、CBF、MTT and TTP of gray matter (frontal/temporal/parietal) and white matter (lateral front/back corner), cerebral blood volume, lentiform nucleus, caudate nucleus, thalamus and internal capsule was measured by perfusion software, and the statistical analysis was carried out. Results 1 The CBF and CBV of cerebral gray matter in normal adults were the highest, and MTT and TTP were the longest, the CBF and CBV of the white matter were the lowest, the MTT and TTP of the lentiform nucleus and caudate nucleus were the shortest. 2 There was no significant difference in CBV, CBF, TTP between the frontal, temporal and parietal lobes(P>0.05), while there was statistically significant difference in MTT(P<0.05). There was no significant difference in CBV, CBF, MTT between the anterior and posterior lateral ventricles of the lateral ventricle(P>0.05), while there was statistically significant in TTP(P<0.05). 3 There was a statistically significant difference between the left and right lateral ventricle CBF (P<0.05), and there was no significant difference in the other parameters of the left and right hemispheres(P<0.05). Conclusion Dual source CT perfusion imaging can reflect the cerebral hemodynamic changes in the normal population, and measured normal adult brain perfusion parameters of the normal reference range, to provide a theoretical basis for the further research of CT perfusion imaging and related research.