Head and Neck Imaging

Cinical Significance of Dual-source CT in the Evaluation of Coronary Intermediate Lesions Comparing with Coronary Angiography*

Author:GAO LI, YUAN Xu-chun, NIE Wei-xia, et al.

affiliation:Department of Radiology, Sun yet-sen Cardiovascular Hospital, Shenzhen 518112, Guangdong Province, China

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Abstract

Objective To investigate the clinical value of dual-source CT in the evaluation of cononary intermediate lesion. Methods 33 cases (41 sites) of coronary intermediate lesions underwent dual-source CT coronary angiography and were confirmed by conventional coronary angiography and Fractional Flow Reserve(FFR) test within one week. According to FFR value, 41 intermediate lesions were divided into two groups: FFR<0.80 group and FFR≥0.80 group. The differences between two groups in plaque burden and vascular remodeling index and the correlation of those parameters with FFR value were analyzed. Results There was statistically significant difference in vascular remolding index between two groups (F=16.45, P<0.05). There was no statistically significant difference in plaque burden between two groups(F=0.53, P>0.05). There was a significant positive correlation between FFR value and RI(r=0.502, P>0.05). Conclusion Dual-source CT coronary angiography may suggest hemodynamic changes of intermediate lesion by evaluating vascular remodeling, and could be helpful in clinical decision-making.

【Keyword】Coronary Intermediate Lesions; Fractional Flow Reserve; Plaque Burden; Vascular Remodeling

【Chart number】R543.3+2

【Document Identification Number】A

【DOI】10.3969/j.issn.1672- 5131.2018.03.017