Head and Neck Imaging

Correlation of Gd-EOB-DTPA-enhanced MRI with Pathologic Gradingin Hepatocellular Carcinoma*

Author:GUO Tian-chang, WU Cai-yun, WEN Yun-xiong, et al.

affiliation:Department of Radiology, the Third People's Hospital of Dongguan, Dongguan 523321, Guangdong Province, China

PDF

Abstract

Objective To investigate the Correlation of Gd-EOB-DTPA-enhanced MRI with Pathologic Grading in Hepatocellular Carcinoma. Methods Twenty patients with twenty-five hepatocellular lesions were evaluated retrospectively. All of the patients had MRI scan, Gd-EOB-DTPA dynamic enhanced scan and hepatobiliary stage enhanced scan.Hepatobiliary phase images on Gd-EOB-DTPA -enhanced MRI were classified into 3 groups: low, mixed signal or iso. Furthermore, correlations between MRI findings and pathological grade for each hepatocellular lesions were performed and statistically evaluated. Results There was a significant correlation between pathological grade and signal intensity in the hepatobiliary phase in 25 cases of hepatocellular carcinoma. There was no significant correlation between the size of the tumor and the pathological grade. Conclusion Signal intensity in the hepatobiliary phase correlated with histological grade. We may have a new way to preliminary judge the pathological grade of HCC according to Gd-EOB-DTPA-enhanced MRI. Gd-EOB-DTPA-enhanced MRI is recommended to apply in patients who were suspected with hepatocellular carcinoma .

【Keyword】Hepatocellular Carcinoma(HCC); MRI;Gd-EOB-DTPA

【Chart number】R735.7

【Document Identification Number】A

【DOI】10.3969/j.issn.1672- 5131.2018.03.020