Objective To explore the application value of MRI multi-parameter scanning in the diagnosis of prostate cancer. Methods The clinical data of 62 patients with suspected prostate cancer treated in our hospital were analyzed retrospectively. All patients were diagnosed with MRI. The MRI examination results were compared with the pathological biopsy results. The sensitivity, specificity and accuracy of MRI in the diagnosis of prostate cancer were analyzed, and the features of MRI images of prostate cancer patients were analyzed. Results The sensitivity, specificity and accuracy of MRI were 90.48%, 85.00% and 88.71% in the diagnosis of prostate cancer. In patients with prostate cancer, T2WI was mostly patchy and abnormal low signals in the periphery of the lesion. In the images of diffusion-weighted imaging (DWI) scan, there was an abnormally high signal at lesion site and the reduced surface diffusion coefficient. Conclusion MRI multi-parameter scanning had important application value in the diagnosis of prostate cancer, and it has high sensitivity, specificity and accuracy, and it can help clinical diagnosis of prostate cancer, therefore it is worthy of clinical promotion.