Head and Neck Imaging
Diagnostic Value of PET or PET/CT for Residual/Recurrent Head Neck Squamous Cell Carcinomas: A Meta-Analysis
Author：ZHANG Rui-yun, QIAO Fei, LI Yong,et al.
affiliation：Departments of CT/MR, The First Affiliated Hospital of the Medical College, Shihezi University, Shihezi 832000, Xinjiang Province, China
PDFAbstract
Objective To review the diagnostic value of PET or PET/CT for residual/ recurrent head neck squamous cell carcinomas systematically. Methods We searched PubMed, The Cochrane Library, CNKI, WanFang Data, VIP, CBM and EMbase from inception to August, 2016. Two reviewers screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the quality of included studies. MetaDiSc 1.4 was used to conduct the meta-analysis. Results Fifteen studies were finally included. For residual/recurrent disease at the primary site, the pooled analysis shown: SEN =0.81[95%CI(0.74,0.86)], SPE =0.81[95%CI(0.78,0.86)], +LR=4.55[95%CI(2.65,7.81)], -LR=0.25[95%CI(0.15,0.43)], DOR=23.42[95%CI(11.45,47.93)] and SROC AUC=0.90. For residual/recurrent disease at the neck nodes, the pooled analysis shown: SEN =0.74[95%CI(0.62,0.83)], SPE=0.88[95%CI(0.84,0.91)], +LR=6.05[95%CI(2.75,13.33)], -LR=0.38[95%CI(0.23,0.64)], DOR =23.40[95%CI(6.20,88.35)] and SROC AUC=0.87. Conclusion PET and PET/CT are highly accurate in detecting residual/recurrent HNSCC.
【Keyword】PET; PET/CT; Squamous Cell Carcinoma of the Head and Neck; Recurrent; Meta-analysis
【Chart number】R73；R74
【Document Identification Number】A
【DOI】10.3969/j.issn.1672-5131.2018.10.004
Chinese journal of CT and MRI
th16Volume， th 10 Issue
2018Year10Month
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