Objective To explore the diagnostic value of CT enterography (CTE) in the inflammatory bowel disease (IBD). Methods 80 cases of patients with probable IBD admitted from January 2015 to December 2017 were selected for the study and were examined by CTE. The comprehensive judgments of clinical manifestations, colonoscopy and histopathological findings were taken as gold standards, and the imaging findings and diagnostic results of CTE were evaluated in the diagnosis of IBD, and the sensitivity, specificity, accuracy, negative predictive value and positive predictive value were calculated. Results CTE showed there were 53 cases of IBD and 27 cases of non-IBD, and the sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 83.02%, 77.78%, 81.25%, 88.00% and 70.00% respectively. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CTE were 83.78%, 88.37%, 86.25%, 86.11% and 86.36% respectively in diagnosis of Crohn's disease, and were 81.25%, 98.44%, 95.00%, 92.86% and 95.45% respectively in diagnosis of ulcerative colitis. Conclusion CTE is an effective method for diagnosing IBD, and it also helps in the differential diagnosis of Crohn's disease and ulcerative colitis.