Head and Neck Imaging

Clinical Value of MRI Combined with Tumor Markers in Preoperative TNM Staging of Patients with Rectal Cancer

Author:SHANG Ya-jun, CHEN Ying, CHEN Ai

affiliation:Department of Radiology, People's Hospital of Chongqing Tongliang District, Chongqing 402560, China

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Abstract

Objective To study the clinical value of MRI combined with tumor markers in preoperative TNM staging of patients with rectal cancer. Methods A total of 200 patients with rectal cancer from December 2015 to December 2017 in the hospital were selected. All patients were detected by MRI, and the serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA19-9) levels were measured. Results With the increase of tumor stage, the levels of CEA and CA19-9 were also gradually increased (P<0.05). Compared with the gold standard, the total accuracy rate in detecting T stage was 83.00% by MRI and was 90.00% by MRI combined with tumor markers (F=4.196, P=0.041). Compared with the gold standard, the total accuracy rate in the detection for N stage was 74.50% by MRI and was 83.50% by MRI combined with tumor markers (F=4.883, P=0.027). Conclusion MRI combined with tumor markers has high accuracy of preoperative staging in patients with rectal cancer.

【Keyword】Tumor Markers; Magnetic Resonance Imaging; Rectal Cancer; Staging Diagnosis

【Chart number】R735.3

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2018.10.042