Objective To explore the clinical application value of analysis of vascular CT combined with color doppler ultrasonography to examine the use of intravenous fistula in different maturation. Methods A total of 60 patients with uremia who came to the hospital in June 2015-2017 June were selected as clinical subjects, all patients underwent vascular CT and color Doppler ultrasonography before and after ostomy. The choice of the available vein for patients with different imaging methods and the internal fistula internal diameter of the internal fistula, the velocity of internal fistula blood flow and the change of internal fistula blood flow were compared. Results The blood vessels CT and color doppler ultrasound can be used to demonstrated arteriovenous fistula of the vein, but the vascular CT examination usable vein number was lower than that using the choice of color doppler ultrasound examination results (P<0.05), statistically significant difference between the groups. Accept colostomy at 4 weeks and 8 weeks after treatment, patients with fistula in diameter, internal fistula blood flow velocity and internal fistula state of blood flow were significantly higher than that of postoperative 1 week (P<0.05), compared with 4 weeks after surgery, postoperative 8 weeks in patients with fistula diameter, internal fistula blood flow velocity and internal fistula blood flow also increased significantly (P<0.05) and significant difference between groups, with statistical significance. Conclusion Vascular CT combined with color Doppler ultrasonography is helpful to select the operating veins of patients who need to be operated by artificial arteriovenous fistulas, and it is also of great significance in assisting the assessment of arteriovenous fistula maturity in patients after stomaostomy.