Head and Neck Imaging

In Vivo Traceing of Umbilical Cord Mesenchymal Stem Cells Labelled by Feridex in Murine Brain*

Author:ZHOU Fen-li, QI Yu-long, MAO Li-jun,et al.

affiliation:Department of Neurology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China

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Abstract

Objective To explore the value of noninvasive traceing of transplanted stem cells in vivo. Methods Feridex labelled umbilical mesenchymal stem cells were transplanted into murine subarachnoid space, and traced by MR. Results Feridex labelled stem cells can immigrate into cerebral tissue, and can be traced in vivo by MR. Conclusion MR can demonstrate the immigration of Feridex labelled stem cells into murine brain. The tracer effect of SWI was superior to T2WI.

【Keyword】Umbilical Mesenchymal Stem Cell Feridex; In Vivo Traceing; Magnetic Resonance Image; Susceptibility-weighted Imaging(SWI)

【Chart number】R68;R32

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2018.10.001