Objective To investigate the clinical value of CT angiography (CTA) in the diagnosis of intracranial aneurysms. Methods The clinical data of 60 patients diagnosed with intracranial aneurysms by operation and digital subtraction angiography (DSA) in our hospital between July 2011 and June 2015 were retrospectively analyzed. All patients received CTA after admission, and the results were compared with those of DSA. The value of CTA in the diagnosis of intracranial aneurysms was analyzed. Results In 60 cases of patients with intracranial aneurysms, there were 73 aneurysms detected by CTA, including single ones in 43 cases and 1 case missed diagnosed; 15 cases of multiple ones (30). 1 case of multiple intracranial aneurysm and one aneurysm with relatively smaller diameter among multiple aneurysms were missed diagnosed. The coincidence rate of CTA in detecting the number of intracranial aneurysms with DSA was 93.59%; There were no significant differences between CTA and DSA in the determination of the minimum diameter, maximum diameter and aneurismal width of intracranial aneurysms (P>0.05). Among different reconstruction methods of CTA, the image quality score of VR reconstruction was the highest. Conclusion CT angiography in the diagnosis of intracranial aneurysm is noninvasive, safe and inexpensive, with high quality image. The diagnostic accuracy is similar to that of DSA, and the clinical application value is high. However, for some patients with aneurysms of which the diameter is relatively smaller and patients who cannot be diagnosed by CTA, DSA screening should be carried out.