Objective To analyze the imaging features of CT and MRI in spleen implantation. Methods The clinical data of 20 patients who underwent abdominal spleen implantation in our hospital were analyzed retrospectively. All patients underwent CT and MRI examination. The CT and MRI findings were summarized and compared with the pathological findings. Results Among the 20 patients with spleen implantation, 4 cases were located in the posterior part of peritoneum, 10 in spleen, 3 cases in spleen and pancreatic tail and 2 cases in multiple spleen implantation. 14 lesions were located in upper abdominal mesenterium and greater omentum area, 10 lesions in the liver, round or quasi-circular and the largest diameter was 1.0cm-5.0cm. The edges were clear; CT plain scan showed slightly low density lesions, compared with normal spleen tissues and the edges were clear. The enhancement at the three phases was homogeneous; MRI scan showed equal or slightly low signal on T1WI sequence positive phase and the antiphase signal decreased or did not change. There were equal signal and high signal on T2WI sequence and banding equal signal in spleen implantation region. Enhanced scan showed inhomogeneous slightly high signal in arterial phase and venous phase, low signal in delayed phase, high signal in envelop delayed phase, high signal in banding shadow in liver. Three-phase scan showed middle high signal in mesenterium and greater omentum. Conclusion CT and MRI imaging can be used as a supplementary means for diagnosis of spleen implantation. The imaging changes and pathological findings of spleen implantation are significantly associated but for some patients whose imaging findings are not specific, biopsy and nuclein examination can be adopted.