Objective To explore the value of MRI assessing liver reserve function and prognosis of liver cancer patients treated with interventional treatment. Methods 49 primary liver cancer patients in our hospital were randomly selected. Magnetic resonance imaging (MRI) scan was finished before the treatment and ADC value was statistically analyzed and MRI imaging features of primary liver cancer was observed. ADC value,indocyanine green 15 min retention rate (ICGR15) and Child-Pugh score before and after interventional therapy and patients' prognosis were statistically analyzed. Results the lesions located in the left hepatic lobe of 22 cases, and right liver lobe of 27 cases. Child-Pugh score and ICGR15 of 3d, 5d, 7d and 14d after interventional treatment was lower than that of before treatment, and the difference was statistically significant (P<0.05). Metastasis and recurrence rate of patients were 44.90% and 48.98% respectively. Patients with metastasis and recurrence had lower ADC value and higher Child-Pugh score and ICGR15 than that of Patients without metastasis and recurrence (P<0.05). Spearman relation analysis results showed MRI detected ADC value of patients with primary liver cancer were all negatively connected with hild-Pugh score and ICGR15, recurrence rate and metastasis rate (r=-0.763,-0.743, -0.685, -0.783, P<0.05). Conclusion MRI tested ADC value in patients with primary liver cancer is lower and connected with liver reserve function and prognosis of patients, thus value tested by MRI assessing liver reserve function and prognosis of liver cancer patients treated with interventional treatment is good.