Objective To analyze the findings and clinical value of multi-slice spiral CT in the diagnosis of congenital bronchial dysplasia. Methods The clinical data of 64 cases of children with congenital bronchial dysplasia who underwent multi-slice spiral CT in our hospital from June 2011 to May 2015 were retrospectively analyzed. The imaging findings were summarized and the diagnostic value was evaluated. Results CT of congenital bronchopulmonary cyst showed round or oval mass shadows, homogeneous density, uniform thickness and smooth edge; CT scan of congenital lobar emphysema showed increase of entrained air content in big lobe, improvement of radiolucency of lung lobe, lung markings, trachea and heart shifting to the left and compressed lung tissues close to normal pulmonary tissues; CT of congenital bronchial atresia showed that the bronchial opening of top-left lung lobe tip of posterior segment was in closed state. From hilus pulmonis to intra-lung lobe, there were radiating columnar signs, in V shape and bronchus was packed and cut off by mucus. There was lung emphysema in the surrounding lung tissues. Conclusion In the clinical diagnosis of congenital bronchial dysplasia, the application of multi-slice spiral CT combined with its post-processing technique can clearly show the location of bronchial lesions and its relationship with adjacent organs. The image quality is good. The qualitative and positioning advantages are significant