Head and Neck Imaging
The Effects of Different Odor Stimulation Paradigms On Olfactory fMRI Study*
Author：ZHANG Hui, SUN Hai-zhen, ZHAO Yan-tong,et al
affiliation：The First Central Clinical College of Tianjin Medical University, Tianjin 300192, China
PDFAbstract
Objective To study the effects of different odor stimulation paradigms on olfactory fMRI results by observing the activation of olfactory central system. Methods Two different olfactory stimulation paradigms olfactory fMRI were executed on the same subjects,and extracted bilateral primary olfactory cortex area as ROI, observing its activation responding and BOLD signal intensity changes, to see whether there are any differences between the two paradigms. Results The ROI area activation responding of both two odor stimulation paradigms of 16 normal volunteers showed no statistical differences (fixed paradigm were 69.00±80.23, trigger paradigm were 102.81±151.44, P values=0.42), and there was no statistical differences between the two average time of BOLD signal intensity curve (P values=0.167). Conclusion No matter what the paradigm is, there should be at least one effective inspiratory phase in the duration of odor stimulation,it should cause the same activation response in the olfactory center. Therefore, different paradigms of olfactory stimulation do not effect on the result of olfactory fMRI.
【Keyword】Olfaction; Functional Magnetic Resonance Imaging; Primary Olfactory Cortex
【Chart number】R339.12
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2016.04.001
Chinese journal of CT and MRI
th14Volume， th 4 Issue
2016Year04Month
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