Head and Neck Imaging

Imaging Features of Langerhans Cell Histiocytosis in Adults

Author:FANG Guo-cheng, WANG Jin-cheng

affiliation:Department of Radiology, Jiangsu Taixing People's Hospital, Taixing 225400, Jiangsu Province, China

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Abstract

Objective To improve the awareness of the imaging features of Langerhans cell histiocytosis(LCH) in different systems. Methods 5 patients of Langerhans cell histiocytosis comfirmed by surgey and histopathology were collected. All imagings were retrospectively analyzed. Results Of these 5 cases, 2 were solitary lesion, and 3 cases were multiple lesions. Involvement of bone lesions show the punched out, soluble osseous bone destruction, and swelling bone destruction, with clear or fuzzy edge, some lesions accompanied by harden edge, and some lesions accompanied with periosteal reaction.1 Lesion occurred in the central nervous system which located at the third ventricle infundibulum, and manifested as a nodule which had a clear edge, and showed significantly enhancement on MRI .The lesion manifested as thickening of the soft tissue when occurred in soft tissue. Conclusion Langerhans cells histocytosis is a relatively rare disease and may involves the whole body, the lesion can be single or multiple, with no specific imaging findings. Therefore, the diagnosis of Langerhan's cell histiocytosis (LCH) is often difficult and delayed.

【Keyword】Langerhans Cell Histiocytosis; Computer Body Image; Magnetic Resonance Imaging

【Chart number】R733;R445.2;R445.3

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2017.11.042