Head and Neck Imaging
Study on Diffusion Kurtosis Imaging in Cerebric Microstructure Changes of Patients with Type II Diabetes Mellitus*
Author：LI Qiu-yu, TAO Jin-de, FU Dong, et al.
affiliation：Department of Radiology, Tungwah Hospital Affiliated to Sun Yat-sen University, Dongguan 523000, Guangdong Province, China
PDFAbstract
Objective To monitor early occult cerebric damage by diffusion kurtosis imaging(DKI)in patients with type II diabetes mellitus. Methods A total of 31 patients with type II diabetes mellitus were taken as the case group(TDM), and 26 age-, sexand education level-matched healthy people were taken as the normal controls(NC). All cases received DKI and evaluation of cognition. The mean kurtosis(MK), the fractional anisotropy(FA) and the mean diffusion(MD) values of different encephalic regions were measured. Results Of the NC group and TDM group, significant differences of MD values(mean MD±SD) were existed in white matter area of occipital lobe, lenticular nucleus, thalamus. Significant differences of MK values(mean MD±SD)were existed in parietal white matter, white matter area of occipital lobe, lenticular nucleus, extra-capsule. But there was no significant difference in FA value between two groups. Conclusion Individuals with type 2 diabetes showed microstructural abnormalities in various encephalic region before shows a sign of cognitive abnormal. These abnormalities can be detected earlier by diffusion kurtosis imaging.
【Keyword】Type II Diabetes Mellitus; Cerebric Microstructure Changes; DKI; Early Detection
【Chart number】R781.6+4
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2017.11.010
Chinese journal of CT and MRI
th15Volume， th 11 Issue
2017Year11Month
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