Head and Neck Imaging
A Study of Brain in Premature Infants at 6 Month After Birth Using Functional Magnetic Resonance Imaging*
Author:WANG Hong-wei, XIANG Kui, GAN Yun-gen
affiliation:Department of Radiology, Shenzhen Children's Hospital, Shenzhen 518038, Guangdong Province, China
PDFAbstract
Objective To study the differences and its significance of ALFF values of the brain using resting-state fMRI(RS.fMRI) in premature and full-term infants at 6 months after birth. Methods 25 premature infants and 21 normal full-term infants were recruited from Shenzhen children Hospital, and screened using RS.fMRI at 6-month after birth. Amplitude of low frequency fluctuation(ALFF) of different brain regions was compared between premature and ful-term infants. Results The RS.fMRI showed that the premature infants had significant decrease of ALFF in cerebellum posterior lobe, frontal Lobe, supp motor Area, while they had significant increase in superior temporal gyrus and anterior cingulate. Conclusion In resting-state, the preterm infants at 6-month after birth have decreased brain activity in many brain regions including cerebellum posterior lobe, frontal Lobe, supp motor Area, however, increased activity in superior temporal gyrus and anterior cingulate might be a kind of adaptation development in the premature brain.
【Keyword】Premature; RS.fMRI; ALFF
【Chart number】R722
【Document Identification Number】A
【DOI】10.3969/j.issn.1672- 5131.2017.01.006
Chinese journal of CT and MRI
th15Volume, th 1 Issue
2017Year01Month
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