Objective To explore acute cerebral ischemia in dynamic susceptibility contrast (DSC) MRI performance and susceptibility weighted imaging (SWI) on scientific and effective image reference for clinical treatment. Methods To choose have been confirmed and the onset time of acute cerebral ischemia in patients with 3D as the object of observation, a total of 44 cases. For patients treated with routine MRI, DSC and SWI examination, imaging observation. Based on the DSC specific into normal perfusion, hypoperfusion, excessive and delayed perfusion in a total of four, at the same time on the basis of the SWI image into vein reduced or increased and normal. Using Mann Whitney method of differential scanning calorimetry (DSC) and SWI two techniques results consistency test analysis, in the SWI shown in lesion and in the contralateral normal brain image area in three regions of interest, and measure the signal strength. Results DSC performance hypoperfusion in 35 cases, including 31 cases showed lesions on SWI vein reduced or have disappeared, and the remaining 13 patients, showed hypoperfusion in 4 cases in the DSC, hyperperfusion six cases, three cases of delayed perfusion, and the display properly on SWI. Consistency between the two technology analysis shows no significant difference (P>0.05), and there was no signal intensity ratio statistically significant difference (P>0.05). Conclusion SWI and DSC comparison, can show cerebral hemodynamic status, it can reflect reperfusion injury, combined with conventional MRI, can provide valuable reference for the treatment and prognosis.