Objective to evaluate multislice CT (MSCT) in diagnosis and identify the value of the small intestinal diseases. Methods a retrospective analysis of our hospital in February 2010-February 2014 scores of the clinical data of 150 patients with suspected small bowel diseases, MDCT and gastrointestinal angiography examination data integrity, to the final clinical diagnosis by contrast, compare multislice computed tomography (CT) and angiography examination of gastrointestinal tract of accuracy, sensitivity, specific degrees. Results of 150 patients with suspected small bowel disease after surgery, endoscopic examination and biopsy pathological examination after comprehensive diagnosis and final diagnosis of small intestinal diseases of 90 cases (60%), MDCT of small intestine disease diagnostic accuracy was 87.3% (131/150), the sensitivity was 78.9% (71/90), 100.0% (60/60), significantly higher than that of the gastrointestinal angiography accuracy rate 64.0% (96/150), the sensitivity of 53.3% (48/90), a specific degree is 80.0% (48/60), differences were statistically significant (P < 0.05). Conclusion MDCT of small intestinal tumor disease, intestinal obstruction, and inflammatory disease diagnosis has the characteristic, diagnostic accuracy, sensitivity and speciality degree were higher, the clear and identify small intestine disease is of important value.