Head and Neck Imaging

Applied Value of MR Diffusion Tensor Imaging in Brain Injury after Asphyxiation in Full Term Newborns*

Author:ZHANG Xiang-ya, CAO Man-rui, DU Mu,et al

affiliation:Department of Radiology, Southern medical university affiliated Shenzhen Maternity& Child Healthcare Hospital, Shenzhen 518028, China

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Abstract

Objective To determine the applied value of MR diffusion tensor imaging(DTI) in brain injury after asphyxiation in full term newborns. Methods 15 infants with HIE, 15 asphyxia infants without HIE and 15 normal infants were studied. All the neonates were examined by conventional MR imaging and diffusion tensor imaging. FA values were calculated in every regions of interest and compared between groups. Results FA values in frontal white matter、posterior limb of internal capsule、splenium of copus callosum、 cerebral peduncle、centrum semiovale of HIE infants were significantly reduced compared with control group(P<0.05); FA values in frontal white matter、posterior limb of internal capsule、splenium of corpus callosum、centrum semiovale of asphyxia infants without HIE were significantly reduced compared with control group (P<0.05); Only in posterior limb of internal capsule, the FA values of HIE infants were significantly reduced compared with asphyxia infants without HIE (P<0.05). Conclusion Diffusion tensor imaging can early detect the brain injury of full term infants after asphyxiation, which may guide the clinician make the plan of treatment to improve the prognosis.

【Keyword】Brain Injury After Asphyxiation; Full Term Infants; Diffusion Tensor Imaging; Fractional Anisotropy

【Chart number】R722.12;R445.2

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672-5131.2015.02.22