Head and Neck Imaging

The Value of Histogram-based Apparent Diffusion Coefficient in Distinguishing Common Pathological Subtypes of Lung Cancer

Author:XU Jian-xing, LIU Liang-qing, WANG Kai-xiang, et al.

affiliation:Department of Radiology, Changzhou Wujin People's Hospital, Changzhou 213002, Jiangsu Province, China

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Abstract

Objective To evaluate whether histogram analysis of apparent diffusion coefficient (ADC) values can be used to differentiate common pathological subtype of lung cancers. Methods Thirty-five lung cancer patients were retrospective1y analyzed.ADC histogram was obtained from the entire tumor volume. ADCmean were obtained in a MR work station through software. Results The ADCmean was significantly lower in small cell carcinomas than that in that non-small cell carcinomas. The ADCmean was significantly lower in squamous cell carcinomas than that in adenocarcinomas. Conclusion Histogram analysis of ADC values in lung cancers has potential for differentiating histologic subtypes, providing information about the entire tumor.

【Keyword】Lung Cancer; Diffusion Weighted Imaging; Apparent Diffusion Coefficient; Histogram

【Chart number】R734.2;R445.2

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2017.11.005