Influence Observation of Dexmedetomidine General Anesthesia on Stress Responses During Operation in Liver Cirrhosis Patients with Hepatectomy
Author：DU Shu-fang, SU Zhi-xia, YANG Hai-tao,et al.
affiliation：Department of Anesthesia, The Second People’s Hospital of Anyang City, Anyang 455000, Henan Province, China
PDFAbstract
Objective To investigate the influence of dexmedetomidine general anesthesia on stress responses during operation in liver cirrhosis patients with hepatectomy. Methods 26 cases with liver cancer in our hospital from December 2015 to December 2016 were selected and divided into observation group and control group according to random number table, 13 cases in each group. Observation group was given intravenous pumping with 0.5ug/kg dexmedetomidine before anesthesia induction. Control group was given equivalent normal saline before induction. Compare the stress hormones level at different time points of the two groups. Results Stress hormones level at the end of operation, 24h after operation, 48h after operation of the two groups were all higher than half hour before surgery. But observation group was lower than control group, the difference was statistic significant (P<0.05). Conclusion It can reduce stress hormones level during operation of liver cirrhosis patients with hepatectomy and clinical applications are promising. Because of small research samples, therefore a lot of samples are needed for further demonstration.
【Keyword】Dexmedetomidine General Anesthesia; Hepatectomy; Perioperative Period; Stress Reaction
【Chart number】R735.7
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2017.06.014
Journal of Rare Diseases
th24Volume， th 6 Issue
2019Year11Month
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