Objective To analyze the clinical features and CT imaging findings of 65 children with adenovirus pneumonia. Methods The clinical data of 65 children with adenovirus pneumonia who were admitted to the hospital from May 2017 to April 2018 were analyzed retrospectively. CT scan was performed, and the clinical features and CT imaging findings of the subjects were analyzed. Results Adenovirus pneumonia could occur in all seasons, especially in winter. Its onset was rapid, and the duration of fever was long. It was characterized by continuous fever, remittent fever, spirits apathy, poor complexion and symptoms of poisoning. The probability of temperature in the range of 40.0-40.9°C was the highest. The main clinical features included fever, pulmonary moist rales and wheezing. Antibiotics plus antiviral drugs were common regimens. CT imaging examination showed lung parenchyma was scattered in the shadow of increased density, both lungs affected, pleural effusion outside the lungs and uneven air inflation in the small airway. Conclusion The clinical features and CT imaging findings of children with adenovirus pneumonia are characteristic. Clinically, children with adenovirus pneumonia can be accurately diagnosed and differentiated, which has a positive effect on reducing the mortality of children.