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Diagnostic Value of Gd-EOB-DTPA Enhanced MRI for Pathological Grading of Liver Cirrhosis

Author：FU Peng

affiliation：Department of Radiology, People's Liberation Army No. 254 Hospital, Tianjin 300143, China

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Abstract

Objective To evaluate the value of Gd-EOB-DTPA enhanced MRI in the pathological grading of liver cirrhosis. Methods 60 patients were divided into fibrosis group, cirrhosis group and normal group. The changes of MRI signal in patients with different degrees of liver diseases were compared. Results (1)Correlation analysis showed that the pathological status of liver was negatively correlated with AEV and CER. The more severe the lesion, the lower the MRI signal intensity and contrast enhancement rate. (2)Correlation analysis showed that there was a significant negative correlation between pathological grading of liver cirrhosis and AEV and CER. The higher the pathological grade of liver cirrhosis, the weaker the AEV and the lower the CER. (3)ROC curve showed that AUC of CER was 0.693 for liver fibrosis and cirrhosis, 0.863 for mild and moderate cirrhosis, and 0.836 for moderate and severe cirrhosis. Conclusion GdEOB-DTPA enhanced MRI has a high diagnostic value for pathological grading of liver cirrhosis, and has a certain clinical value.

【Keyword】Cirrhosis; Liver Fibrosis; Gadolinium Acid Two Sodium

【Chart number】R657.3+1

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2018.12.031

Chinese journal of CT and MRI

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