Head and Neck Imaging

The CT Features of Children Neuroblastoma with Bone Metastasis

Author:ZHANG Long, YANG Ying, WANG Zhi-peng, et al.

affiliation:Department of Magnetic Resonance, Qinhuangdao Military Hospital, Qinghuangdao 066000, Hebei Province, China

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Abstract

Objective To explore the CT features of children neuroblastoma with bone metastasis. Methods The clinical data of 22 patients with NB with bone metastasis were analyzed and their CT features were analyzed. Results There were 19 cases of solitary lesion and 3 cases of multiple lesions, 6 cases located at adrenal gland and 4 cases located at vertebral body. All the 22 cases were accompanied by bone metastases, including the spine, ilium, ribs, sternum and multiple metastases. At the same time, 3 cases were accompanied with liver metastasis and 4 cases with lymph node metastasis. NB larger tumors from the primary lesion and uneven density, with calcification and necrosis, uneven enhancement scanning in light-severe reinforcement, bone metastases are characterized by dissolving osseous bone destruction, some lesions of soft tissue mass with calcification or vertical spicules. Hepatic and lymph node metastases were not evenly distributed, and the enhanced scan was annular or inhomogeneous. Conclusion The CT features of NB primary lesions in children have certain characteristics, and bone metastasis was mainly caused by osteolytic destruction, and CT has important value in detecting them.

【Keyword】Children; Neuroblastoma; Bone Metastases; Computer Body Photography

【Chart number】R814;R730

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2018.12.042