Objective To explore the features of pulmonary sclerosing hemangioma by 64-row spiral CT, in order to provide evidence for clinical diagnosis. Methods The 64- row spiral CT findings and clinical data of 22 cases of PSH which were histologically confirmed ,were retrospectively analyzed. Results All patients were female,aged 24-59 years old, average age was 42.3±13.2 years old. All cases were signal lesion. Distribution of lesions was as below: 5 cases in the upper lobe of right lung , 3 in the middle lobe of right lung, 6 in the lower lobe of right lung, 2 in the upper lobe of left lung, 6 in the lower lobe of left lung. No spicule sign was found in all cases. Relative characteristic signs were as below: air crescent sign in ten cases(45.5%), halo sign in thirteen cases(59.1%), welt vessel syndrome in seven cases(31.2%), moreover the lesion was closer to the lung hilus, the welt vessel syndrome was more obvious. 10 cases were associated with punctuate or patchy calcification. All cases were enhanced obviously after injection of iodinated contrast agent , among them , homogeneous enhancement was found in 7 cases, which CT value increased 34±12Hu in the arterial phase, 62±23Hu increased in the delayed phase; inhomogeneous enhancement was found in 11 cases, which CT value increased 23±14Hu in the arterial phase, 54±18Hu increased in the delayed phase; delayed enhancement was found in 4 cases. Conclusion Pulmonary sclerosing hemangioma is more common in female, there are several relatively specific CT manifestations, and CT scanning has certain diagnostic value.