Objective To determine the CT and MRI findings of acute cerebral infarction by venomous snake bitten. Methods The imaging findings of 7 patients with acute cerebral infarction by venomous snake bitten were analyzed retrospectively with literatures review. Results 2 case was bitten by Pit viper. 4cases were bitten by Russell's viper and 1 case was unknown viper. One leaf or multiple leaves cerebrum occurred frequently. Acute obstruct with multiple mottling, patchy, or schistose. 84 acute cerebral infarction in 21 leaves cerebrum of 7 cases, parietal lobe(26/84,30.95%),frontal lobe(19/84,22.62%),occipital lobe(21/84,25%),temporal lobe(16/84,19.05%),basal ganglia(2/84,2.38%), Infarct with hemorrhages in 1 case. Conclusion Combination with the history of venomous snake bitten, the acute cerebral infarction could be diagnosed by CT and MRI, which had great value in the clinical treatment planning for identifying the intracal hemorrhage.