目的 观察参芎注射液治疗缺血性脑血管疾病的疗效并分析其作用机制。方法 80例缺血性脑血管疾病患者进行研 究，采用随机数字表法将受试者随机分为实验组、对照组各40例,两组均予以奥扎格雷注射液静脉滴注治疗，实 验组在此基础上予以参芎注射液。比较治疗前、治疗2周后两组患者各侧支循环[大脑中动脉(MCA)、大脑后动脉 (PCA)、大脑前动脉(ACA)]血流速度以及神经功能缺损(NIHSS)评分变化。结果 两组患者治疗前侧支循环MCA、 PCA、ACA血流速度对比差异均无统计学意义(P＞0.05)，治疗2周后，实验组MCA血流速度高于对照组(P＜0.05)， PCA、ACA血流速度均低于对照组(P均＜0.05)；两组治疗前NIHSS评分对比差异无统计学意义(P＞0.05)，治疗2周 后，实验组NIHSS评分低于对照组(P＜0.05)。结论 参芎葡萄糖注射液可有效促进缺血性脑血管疾病患者的侧支循 环建立，改善其侧支循环血液，进而有利于神经功能损伤恢复。

Objective To observe the efficacy of Shenxiong injection on ischemic cerebrovascular diseases and analyze its role mechanism. Methods 80 patients with ischemic cerebrovascular diseases were enrolled in the study, and the subjects were randomly divided into experimental group and control group according to the random number table method, with 40 cases in each group. The two groups were given intravenous infusion of ozagrel injection, and experimental group was given Shenxiong injection on this basis. Changes of blood flow velocities of collateral circulation[middle cerebral artery(MCA), posterior cerebral artery(PCA), anterior cerebral artery(ACA)]and neurological deficit (NIHSS) score were compared between the two groups before treatment and after 2 w of treatment. Results There were no significant differences in blood flow velocities of MCA, PCA and ACA between the two groups before treatment(P>0.05). After 2 w of treatment, the blood flow velocity of MCA in experimental group was higher than that in control group(P<0.05) while the blood flow velocities of PCA and ACA were lower than those in control group(all P<0.05). There was no significant difference in the NIHSS score between the two groups before treatment (P>0.05). After 2 w of treatment, the NIHSS score in experimental group was lower than that in control group(P<0.05). Conclusion Shenxiong glucose injection can effectively promote the establishment of collateral circulation and improve the collateral circulation blood in patients with ischemic cerebrovascular diseases, thus helping the recovery of neurological deficit.