目的 探究窄谱中波紫外线(NB-UVB)联合复方卡力孜然酊(KT)治疗白癜风的效果。方法 选取150例白癜风患者为受 试对象，依照随机数表将其分为联合组(n=75)与对照组(n=75)。联合组予以NB-UVB照射联合外搽KT治疗，对照组仅 予以NB-UVB照射治疗。比较两组患者治疗前及治疗3个月后血清白细胞介素-17(IL-17)水平、皮损区面积、自信心 [Rosenberg自信心评分量表(RSES)]变化情况，分析两组治疗效果及治疗过程中不良反应发生情况差异。结果 治疗 3个月后，两组患者血清IL-17水平、皮损区面积、RSES评分均较治疗前获得明显改善，且联合组改善效果更佳(P均 ＜0.05)；联合组患者治疗效果显著优于对照组(P＜0.05)，而组间不良反应发生率比较则均无统计学意义(P均＞ 0.05)。结论 NB-UVB联合KT方案可安全有效的应用于白癜风治疗。

Objective To explore the effecst of narrow-band ultraviolet (NB-UVB) combined with compound Kaliziran tincture (KT) in the treatment of vitiligo. Methods A total of 150 patients with vitiligo were selected as subjects and were divided into combined group (n=75) and control group (n=75) according to the random number table method. Combined group was given NB-UVB irradiation combined with external application of KT, and control group was only treated with NB-UVB. The changes of serum interleukin-17 (IL-17) level, skin lesion area and self-esteem [Rosenberg SelfEsteem Scale (RSES)] were compared between the two groups before and after 3 months of treatment. The treatment effects and occurrence of adverse reactions during treatment were analyzed in the two groups. Results After 3 months of treatment, the serum IL-17 level, skin lesion area and RSES score in the two groups were significantly improved compared with those before treatment, and the improvements were better in combined group (all P<0.05). The treatment effects in combined group were significantly better than those in control group (P<0.05), and there was no statistically significant difference in the incidence rate of adverse reactions between the groups (all P>0.05). Conclusion NB-UVB combined with KT regimen can be safely and effectively applied to vitiligo treatment.