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实时超声弹性成像对鉴别甲状腺结节良恶性的诊断价值

作者:兰方荣

所属单位:湖北省武汉市第一医院体检中心 (湖北 武汉 430030)

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摘要

目的 探讨实时超声弹性成像对鉴别甲状腺结节良恶性的诊断价值。方法 选取2014年3月-2015年7月我院行甲状腺 结节良恶性鉴别的患者64例,共85个甲状腺结节病灶,全部患者均接受常规超声、实时超声弹性成像检查,并将两 种检查方法的结果与术后病理结果进行对照。结果 以术后病理结果为金标准,检查确诊良性结节62个,恶性结节 23个;常规超声诊断良性结节41个,恶性结节12个;实时超声弹性成像诊断良性结节56个,恶性结节21个;超声弹 性成像检查敏感性、特异性及诊断符合率均较常规超声高(P<0.05)。结论 采用实时超声弹性成像鉴别甲状腺结节 良恶性,其敏感性、特异性及诊断符合率优于常规超声,故临床诊断价值较高。

Objective To explore the diagnostic value of real-time ultrasonic elastography in identification of benign and malignant thyroid nodules. Methods 64 cases of patients with benign and malignant thyroid nodules in our hospital from March 2014 to July 2015 were selected, with a total of 85 thyroid nodules. All the patients received routine ultrasound and real-time ultrasonic elastography. The results of the two methods were compared with the pathological results after operation. Results Postoperative pathological findings were the gold standard, 62 cases were confirmed as benign nodule, and 23 cases were confirmed as malignant nodule. Routine ultrasound diagnosis that there were 41 benign nodules, 12 malignant nodules. Real-time ultrasound elastography that there were 56 benign nodules and 21 malignant nodules. The sensitivity, specificity and diagnostic accuracy of ultrasound elastography were higher than those of routine ultrasound (P<0.05). Conclusion Real-time ultrasonic elastography in identification of benign and malignant thyroid nodules, the sensitivity, specificity and diagnostic coincidence rate are better than those of routine ultrasound, with higher clinical diagnostic value.

【关键词】实时超声弹性成像; 甲状腺结节良恶性; 常规超声

【中图分类号】R335+.2

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2019.02.003

前言

甲状腺结节是临床上常见的肿瘤科疾病,多见于 中年女性人群。该疾病发病早期症状较不明显,若不 及时就诊,导致病情继续恶化,可产生颈部胀痛、吞 咽困难等症状,严重时可损害呼吸道功能。而一旦甲 状腺结节发生癌变并向远处扩散转移,将会侵犯其食 道、气管,甚至威胁患者生命。因此,对患者甲状腺 结节良恶性进行早期鉴别诊断关系到预后情况。目 前,常规超声检查是甲状腺结节良恶性鉴别诊断的主 要手段之一,具有经济实惠、无创、无辐射及动态连 续扫查等优点。但有研究表明[1],少数甲状腺良恶性 结节存在相似的声像图特征及血流信号,故难以对其 进行正确诊断。实时超声弹性成像是近年来开始逐渐 临床应用的新型技术,也是超声鉴别甲状腺结节良恶性方面的热门议题。本研究将探讨实时超声弹性成像 对鉴别甲状腺结节良恶性的诊断价值,现报道如下。