摘要
目的 探讨天麻素注射治疗系统性眩晕(SV)疗效及对椎-基底动脉血流动力学的影响。方法 选取我院于2017年3 月-2018年3月期间收诊100例SV患者,按随机数表法分为两组。对照组采用盐酸倍他司汀注射液,观察组在对照组 基础上加上天麻素注射治疗,两组均持续用药2周。记录两组患者治疗效果,检测两组患者治疗前后血流动力学指 标情况。结果 观察组患者总有效率(90.0%)高于对照组(72.0%),差异有统计学意义(P<0.05);与治疗前相比,两 组患者治疗后左椎动脉、右椎动脉和基底动脉血流速度均提高,差异有统计学意义(P<0.05);观察组与对照组比 较,左椎动脉、右椎动脉和基底动脉血流速度提高更多,差异有统计学意义(P<0.05)。结论 天麻素注射治疗治疗 SV患者的效果显著,可有效改善患者的椎-基底动脉血流动力学状况。
Objective To investigate curative effect of gastrodin injection on systemic vertigo (SV) and its influence on vertebrobasilar hemodynamics. Methods 100 patients with SV who were admitted to the hospital from March 2017 to March 2018 were enrolled. They were divided into two groups according to the random number table method. The control group was treated with betahistine hydrochloride injection, while the observation group was additionally treated with gastrodin injection on the basis of the control group. The medication in both groups lasted for 2 weeks. The curative effects of the two groups were recorded. The hemodynamic indexes of the two groups were measured before and after treatment. Results The total response rate in the observation group was higher than that in the control group (90.0% vs 72.0%) (P<0.05). The blood flow velocity left vertebral artery, right vertebral artery and the basilar artery and the basilar artery in both groups were increased after treatment (P<0.05). The increase of the above indexes in the observation group was more than that in the control group (P<0.05). Conclusion The curative effect of gastrodin injection is obvious on SV patients, which can significantly improve their vertebrobasilar hemodynamics.
【关键词】天麻素注射液;系统性眩晕;盐酸倍他司汀注射液
【中图分类号】R255.3
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2019.02.011
前言
眩晕病发病率高同时病因复杂,多见于发热性疾 病、脑动脉粥样硬化、颅脑外伤等[1]。而SV是由前庭 系统发生病变引起,通常伴有平衡、听力障碍及眼球 震颤等症状,按照发生病变部位不同有中枢性眩晕及 周围性眩晕两种[2]。西医治疗通常使用扩张脑血管、 降低脑血管中血液粘稠程度类药物通过改善血液循环 供给进行治疗,但此类对症药物在患者康复后容易复 发,同时伴有不良反应[3]。 中医中认为眩晕病位在脑部,与经络气血、肝肾 脾部位有关[4],天麻素是中药天麻中提取有效成分, 在临床上对各种眩晕症状都有较好疗效。本文通过研 究天麻素注射治疗SV疗效及对椎-基底动脉血流动力学的影响,以期在治疗SV上作出指导,现报告如下。
罕少疾病杂志
第26卷, 第 2 期
2019年03月
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