摘要
目的 探讨和分析心外膜脂肪组织厚度对冠心病的预测价值。方法 研究选择2015年8月-2017年7月间在我院心内科 进行诊治的152例患者作研究对象,遵循患者的患病情况分甲组、乙组。甲组是冠心病患者,为76例,乙组是非冠 心病患者,为76例。所有患者均进行血液标本测定、冠状动脉造影检查、超声检查,评价甲乙两组患者的相关指标 水平。结果 甲乙两组患者的左心室射血分数水平、C反应蛋白水平、高密度脂蛋白胆固醇水平、白介素10水平、甘 油三酯水平间差异对比不具有统计学意义(P>0.05)。甲组患者的心外膜脂肪组织厚度水平、总胆固醇水平、低 密度脂蛋白胆固醇水平、冠状动脉狭窄程度均大于乙组患者,差异对比具有统计学意义(P<0.05)。心外膜脂肪 组织厚度水平同冠状动脉病变程度正相关。结论 在冠心病的预测中,心外膜脂肪组织厚度的价值很高,可预测出 患者病情的严重程度,方法简单无创,临床应用性很强。
Objective To investigate and analyze the predictive value of epicardial adipose tissue thickness in patients with coronary heart disease. Methods 152 cases of August 2015 -2017 year in July were treated in the Department of Cardiology in our hospital patients as the research object, according to the prevalence of patients with group A, group B, group A patients of coronary heart disease, 76 cases of group B non coronary heart disease patients, 76 cases. All patients were measured blood samples, coronary angiography, ultrasonography, and evaluation of the two groups were related to index level. Results Two groups of patients with a left ventricular ejection fraction, C reactive protein, high density lipoprotein cholesterol, interleukin 10 the level of triglyceride level difference comparison was not statistically significant (P>0.05). The level of the group of patients with epicardial adipose tissue thickness, total cholesterol, low density lipoprotein cholesterol, coronary artery The degree of vein stenosis were higher than group B patients, compared the difference was statistically significant (P<0.05). Positive correlation with epicardial adipose tissue thickness and the severity of coronary artery disease. Conclusion In the prediction of coronary heart disease, epicardial adipose tissue thickness value is very high, can predict the severity of patients. The method is simple and noninvasive, the clinical application is very strong.
【关键词】冠心病;心外膜;脂肪组织;厚度;预测价值;冠状动脉造影
【中图分类号】R541.4
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.04.007
前言
在临床上,冠心病重要的危险因素是内脏脂肪组 织。有研究发现,患者的性别、年龄、腹型肥胖、种 族等对于冠心病产生的影响要大于体质指数[1]。而心 外膜脂肪组织是心脏、冠状动脉表面包裹的脂肪组 织[2]。心外膜脂肪组织同腹部脏器的脂肪组织存在同 源性,均是起源于婴儿期棕色脂肪组织[3]。所以,可 推测出心外膜脂肪组织同腹部脂肪组织存在类似效 应,很可能也是冠心病的一种危险因素[4]。为了探讨 和分析心外膜脂肪组织厚度对冠心病的预测价值,研究选择2015年8月~2017年7月间在我院心内科进行诊 治的152例患者作研究对象,以下为研究内容。
罕少疾病杂志
第25卷, 第 4 期
2019年11月
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