目的 探讨论胎膜早破孕妇白细胞介素-6(IL-6)的表达水平及其临床意义。方法 选取我院产科在2015年1月至 2016年2月收治的70例行剖宫产分娩的胎膜早破孕妇作为观察组，另选取29例同期在我院住院的非胎膜早破的 孕妇，对比两组孕妇血清IL-6的表达水平。结果 观察组血清IL-6水平明显高于对照组[(0.71±0.12)µg/L vs (0.42±0.09)µg/L](P<0.05)；足月组血清IL-6水平明显低于未足月组[(0.64±0.10)µg/L vs (0.81±0.15)µg/ L](P<0.05)；感染组患者血清IL-6水平明显高于未感染组(P<0.05)；重度感染血清IL-6水平明显高于轻度感染与中 度感染(P<0.05)；中度感染血清IL-6水平明显高于轻度感染(P<0.05)。结论 血清IL-6的表达水平是用于检测胎膜 早破绒毛膜羊膜炎感染的较好指标

Objective To study the expression level and clinical significance of interleukin-6 (IL-6) in pregnant women with premature rupture of membranes. Methods From Jan. 2015 to Feb. 2016, a total of 70 cesarean section pregnant women with premature rupture of membranes in our hospital were selected as observation group, at the same time another 29 normal pregnant women were selected as control group. The IL-6 levels in the two groups were compared. Results The serum IL-6 level in the observation group was (0.71±0.12) µg/L which was significantly higher than that in the control group (0.42±0.09)µg/L(P<0.05), the serum IL-6 level in the mature group was (0.64±0.10) µg/L which was obviously lower than that in the premature group (0.81±0.15) µg/L (P<0.05), the level of serum IL-6 in the infected group was significantly higher than that in the uninfected group (P<0.05), the level of serum IL-6 in the severe infected patients was significantly higher than that in the mild and moderate infected patients(P<0.05), the serum IL-6 level in the moderate infected patients was significantly higher than in the mild infected patients(P<0.05). Conclusion The expression level of serum IL-6 is a better indicator for detecting the chorioamnionitis of premature rupture of membranes.