目的 分析ICU重症患者接受集束化护理后导管相关感染的发生情况。方法 选取我院收治的ICU重症病患68例，随机 分为常规干预组、集束化干预组各34例，比较两组的导管相关性感染率、插管时间、ICU住院时间以及护理效果。 结果 ①导管相关性感染率：常规干预组为20.59%，集束化干预组为2.94%，前者高于后者，组别间具有显著差异性 (P＜0.05)；②就住院、插管时间而言，集束化干预组小于常规干预组，两组对比有差异(P＜0.05)；③集束化干预 组各项护理指标分值均比常规干预组高，两组数据存在统计学差异(P＜0.05)。结论 集束化护理的实施能降低ICU 重症病患导管相关性感染率，缩短ICU住院时间，护理效果显著，值得临床推广。

Objective To analyze the effect of cluster-based nursing on catheter-related infection rate in ICU severe patients. Methods A total of 68 ICU severe patients in our hospital were taken as the clinical objects, and they were randomly divided into routine intervention group (34 cases) and cluster-based intervention group (34 cases). The catheterrelated infection rates, intubation time, ICU hospital stay and nursing effects in the two groups were compared. Results The catheter-related infection rate in the routine intervention group was 20.59% which was obviously higher than that in the cluster-based intervention group 2.94%, and their difference was statistically significant(P<0.05), the intubation time and hospital stay in the routine intervention group were obviously longer than those in the clusterbased intervention group, and their differences were statistically significant(P<0.05), the scores of nursing indicators in the cluster-based intervention group were higher than those in the routine intervention group, and their differences were statistically significant(P<0.05). Conclusion The cluster-based nursing which has significant nursing effect in ICU severe patients, can not only reduce the incidence of catheter-related infection, but also shorten the ICU hospital stay. Thus, it is worthy of clinical application.