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·腹部疾病·

原发性膀胱印戒细胞癌1例并文献复习

作者:许晖阳 王道虎

所属单位:中山大学附属第一医院泌尿外科 (广东 广州 510080)

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摘要

目的 探讨原发性膀胱印戒细胞癌的临床特征。方法 报告1例原发性膀胱印戒细胞癌患者的临床资料并文献复习。 患者行根治性膀胱全切术+回肠代膀胱术。结果 术后病例理告为膀胱印戒细胞癌。患者术后5个月肿瘤腹腔广泛转 移死亡。结论 原发性膀胱印戒细胞癌是一类恶性程度高且组织类型少见的膀胱肿瘤,进展快,局部浸润性生长, 有早期扩散转移倾向,预后差。

Objective To investigate the clinical features of primary signet-ring carcinoma of urinary bladder(PSCC). Methods A case of PSCC was studied retrospectively by reviewing medical literature. Radical cystectomy and Bricker operation was performed. Results The histopathological diagnosis on the surgical specimen showed signet-ring carcinoma. This Patient died 5 months after operation. Conclusion PSCC is an exceedingly rare and aggressive variant of primary bladder carcinoma. This tumor initially presents as a high-grade, high-stage lesion and diffusely invades the bladder wall with poor prognosis.

【关键词】膀胱肿瘤;印戒细胞癌

【中图分类号】R737.14

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2017.05.013

前言

原发性膀胱印戒细胞癌(primary signet-ring cell carcinoma of the urinary bladder,PSCC) 是膀胱腺癌的一种,印戒细胞癌原发于膀胱非常罕 见。PSCC临床表现无特异性,浸润性强,恶性程度较 高,早期诊断困难,预后较差。本文报道我院泌尿 外科收治的1例原发性膀胱印戒细胞癌,结合文献资 料,对其组织来源、病理特征、诊断、治疗及预后进 行探讨,以提高对PSCC的认识。