目的 比较奈达铂、替吉奥同步化疗与三维适形放疗治疗局部食管癌晚期患者的近期临床疗效。方法 选取2016年1 月-2017年1月我院收治的局部食管癌晚期患者60例，并采用数字表法随机分组为观察组和对照组，各30例。观察组 患者给予同步化疗并三维适形放疗，对照组患者给予三维适形放疗，观察两组患者经治疗后的近期临床疗效情况。 结果 对两组患者在不同方法治疗后的效果进行探讨分析，观察组患者的总有效率（96.67%）明显高于对照组的总 有效率（66.67%），差异具有统计学意义（P <0.05）；观察组用药不良反应为16.67%，对照组为10.00%，两组用 药不良反应对比,差异无统计学意义（P>0.05）。结论 同步化疗并三维适形放疗在局部食管癌晚期患者的应用具有 重要价值，可提升患者近期治疗效果，且其所发生的毒副反应可耐受，值得推广。

Objective To compare the short-term effects between Nedaplatin, Tegafur Gimeracil Ote chemoradiotherapy and three dimensional conformal radiation therapy in treating local advanced esophageal cancer. Methods 60 cases with local advanced esophageal cancer in our hospital from January 2016 to January 2017 were selected according to random number table and divided into observation group and control group, 30 cases in each group. Observation group was given chemoradiotherapy and three dimensional conformal radiation therapy, control group was given three dimensional conformal radiation therapy. Compare the short-term effects of the two groups after treatment. Results Compare the effects of the two groups after different methods, total efficiency of observation group (96.67%) was higher than control group (66.67%), the difference was statistic significant (P<0.05), adverse reaction rate of observation group and control group were 16.67% and 10.00%, the difference was not statistic significant (P>0.05). Conclusion Chemoradiotherapy and three dimensional conformal radiation therapy have significant value in treating local advanced esophageal cancer, they can improve short-term effects of patients and toxicity reaction is tolerable. It is worthy of wide application.