摘要
目的 在儿童肾母细胞瘤患者的诊断中应用多排螺旋CT,并分析其临床应用价值。方法 选择我院在2015年3月至 2016年5月期间接收的46例儿童肾母细胞瘤患者作为试验的研究对象,并对其进行回顾性分析。所有患者均经过手 术或者穿刺活检病理诊断检查。患者在术前均接受超声检查和多排螺旋CT检查,将超声检查结果作为对照组,多 排螺旋CT检查结果作为观察组,比较两种检查方法的灵敏度和特异性。结果 超声检查诊断肾母细胞瘤的阳性率为 (52.17%)与CT检查的阳性率(63.04%)相比,无明显差异,差异在统计学上无意义(P>0.05),CT对于诊断儿童肾母细 胞瘤的敏感度、特异性分别为(96.55%)、(94.12%),与超声诊断肾母细胞瘤的特异度(41.18%)、敏感性(58.33%)相 比,差异明显,在统计学上有意义(P<0.05),结论 在骨髓增生异常综合征的治疗中,三氧化二砷与HAG方案的治疗 效果相近,但是三氧化二砷的不良反应发生较少,且程度较轻,所以临床推荐使用三氧化二砷治疗骨髓增生异常综 合征。
Objective To investigate the application value of MDCT on diagnosing nephroblastoma. Methods 46 cases with nephroblastoma in our hospital from March 2015 to May 2016 were selected and retrospectively analyzed. All patients were given surgery or aspiration biopsy. They were all given ultrasonic testing and MDCT before surgery, ultrasonic testing results were seen as control group, MDCT results were seen as observation group, compare the sensibility and specificity of the two methods. Results Positive rate between ultrasonic testing (52.17%) and MDCT (63.04%) had no obvious difference, the difference was not statistic significant (P>0.05), sensibility and specificity between ultrasonic testing [(96.55%),(94.12%)] and MDCT [(41.18%),(58.33%)] had obvious difference, the difference was statistic significant (P<0.05). Conclusion In the treatment of MDS, arsenic trioxide and HAG regimen has similar effect, but arsenic trioxide has less adverse reactions and is worthy of clinic use.
【关键词】多排螺旋CT;肾母细胞瘤
【中图分类号】R322.6+1
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2017.03.015
前言
肾母细胞瘤是一种常见的泌尿系统的恶性肿瘤, 其发病人群主要集中在婴幼儿,一般是单侧肾发病, 目前关于此疾病病因尚未明,可能与基因的丢失或者 突变有关。儿童肾母细胞瘤与成人的症状有所不同, 其较少表现为血尿,多数患者是由发腹部包块而就 诊,少数表现为消化道症状,发热等[1]。临床上对于 患者综合治疗,有较高的治愈率,但是其预后与肿瘤 发展分期有关,所以准确早期地进行肾母细胞瘤的诊 断至关重要,现为了多排螺旋CT诊断儿童肾母细胞瘤 的应用价值,特对我院46例儿童肾母细胞瘤患者进行 试验研究,报道如下。
罕少疾病杂志
第24卷, 第 3 期
2019年11月
相关文章