目的 探讨新生儿缺氧缺血性脑病的CT改变及诊断价值。方法 对45例缺氧缺血性脑病（HIE）的临床及CT影像资料 进行回顾分析。结果 CT能够清楚显示颅脑缺氧缺血后引起的脑实质改变，病变累及范围及程度，以及颅内出血、 畸形等。结论 运用CT检查技术，能够明显提高临床对HIE诊断的准确率，并对脑水肿、梗死及颅内出血的部位、范 围及类型都具有明确的诊断价值，对HIE预后有着十分重要的临床意义。

Objective To observe the change of neonatal hypoxic ischemic encephalopathy (HIE) of CT and diagnostic value. Methods The clinical and MSCT imaging data of 45 cases with HIE were retrospectively analyzed. Results CT could clearly show the brain parenchymal changes caused by brain ischemia and hypoxia, range and degree of involvement, and intracranial hemorrhage, deformity. Conclusion The use of CT technology, could significantly improve the clinical accuracy of HIE diagnosis, and would have important diagnostic values on cerebral edema, infarction, intracranial hemorrhage and parts of the scope and type, and clinical significance on the prognosis of HIE.