目的 探讨血液灌流串联血液透析治疗对甲状旁腺激素的影响。方法 选取我院从2015年1月到2016年1月入院治疗的 90例尿毒症患者做为研究对象。按照入院顺序随机分为观察组45例与对照组45例，观察组患者应用血液灌流串联血 液透析治疗，对照组患者仅应用血液透析治疗。比较两组患者的透析效果及透析前后患者甲状旁腺激素变化情况。 结果 观察组患者的治疗后临床症状改善优于对照组患者，差异具统计学意义(P＜0.05)。两组患者治疗前后Ca2+浓 度无显著变化，观察组患者透析治疗后血清PTH、P3+两项指标均显著下降，对照组患者透析治疗后血清PTH、P3+两 项指标均显著升高，差异具统计学意义(P＜0.05)。结论 应用血液灌流串联血液透析治疗尿毒症患者，可显著提高 透析效果，降低患者甲状旁腺激素水平，减轻透析所致的皮肤瘙痒及骨痛等副反应，值得临床广泛推广应用。

Objective To investigate the effect of the series of hemoperfusion hemodialysis treatment on parathyroid hormone. Methods From January 2015 to January 2016, 90 cases of uremic inpatients were selected as research objects. According to admission, patients were divided into observation group and control group with 45 cases of each group randomly. Patients in observation group were underwent hemoperfusion in series hemodialysis treatment, while only hemodialysis were underwent in control group. The effect of dialysis and the change of parathyroid hormone before and after dialysis were compared among groups. Results The observed group was better clinical improvement than control group after treatment, and the difference was statistically significant (P<0.05). Before and after treatment in two groups Ca2 + concentration was no significant change in serum PTH, P3 + two indicators were significantly higher in the control group of patients on dialysis, serum PTH, P3 + two indicators decreased significantly after the observation of patients on dialysis, the difference statistically significance (P<0.05). Conclusion Hemoperfusion series hemodialysis in patients with uremia can significantly increase the effect of dialysis, reduce parathyroid hormone levels, relieve side effects such as skin itch and ostalgia caused by dialysis, is worthy for wider application.