摘要
目的 探讨原发性醛固酮增多症的诊断。方法 回顾性分析我院从2012年8月到2015年10月手术病理确诊的42例原发 性醛固醇增多症患者的临床资料。统计患者血浆醛固酮(PAC)与肾素比值(ARR)及血浆醛固酮指标用于临床诊断的 检出率及诊断符合率,阳性率等。结果 女性原发性醛固醇增多症患者其血钾水平低于男性,差异具统计学意义(P <0.05)。当ARR高于30时,原发性醛固酮增多症的检出率高于ARR>30且PAC>415pmol/L,差异具统计学意义(P <0.05)。结论 通过监测疑似PA患者值的变化,当ARR高于30时,原发性醛固酮增多症的检出率为83.33%,高于其 他临床指标检出率,值得临床广泛推广应用。
Objective To investigate the diagnosis of primary aldosteronism. Methods A retrospective analysis of 42 patients’ clinical data in our hospital from August 2012 to October 2015, which were confirmed as primary aldehyde steroids increase by pathological. Clinical data statistics in patients with plasma aldosterone (PAC) and renin ratio (ARR) and plasma aldosterone index for clinical diagnosis rate and the diagnosis coincidence rate, positive rate. Results Female patients with primary aldehyde steroids increase their potassium levels lower than men, the difference was statistically significant (P<0.05). When ARR is higher than 30, primary aldosteronism detection rate in ARR> 30 and PAC> 415pmol / L, the difference statistically significant (P<0.05). Conclusion By monitoring changes in patients with suspected PA value, when the ARR is higher than 30, primary aldosteronism detection rate of 83.33%, higher than the detection rate of other clinical indicators, it is worthy of wider application.
【关键词】原发性醛固酮增多症;诊断;治疗
【中图分类号】552
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2016.03.013
前言
原发性醛固酮增多症(primary aldosteronism, PA)发病时机体大量分泌醛固酮,并抑制肾素生成, 导致患者出现高血压、低血钾等临床病理表现[1]。回 顾性分析我院从2012年8月到2015年10月手术病理确 诊的42例原发性醛固醇增多症患者的临床资料,现报 道如下。
罕少疾病杂志
第23卷, 第 4 期
2019年11月
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