目的 探讨MRI增强扫描对评价乳腺癌根治术后脑转移的临床价值。方法 回顾性分析32例经临床病理证实乳腺癌根 治术后脑转移患者的临床和MRI资料，32例均行常规T1WI、T2WI平扫、液体衰减反转恢复 (FLAIR)和扩散加权成像 (DWI)及T1WI增强扫描，分析MRI各成像序列对转移病灶的显示能力。结果 各序列扫描共显示转移病灶284个，病灶 转移至脑实质、脑膜。T1WI为等或低信号，T2WI、FLAIR、DWI为等或高信号，信号均匀或不均匀，增强扫描明显强 化，强化模式多样，瘤周不同程度水肿。增强扫描对转移病灶的检出率明显高于其他扫描序列，差别具有统计学意 义(P＜0.05)。结论 MRI多序列扫描有利于乳腺癌根治术后脑转移瘤的诊断及鉴别诊断，增强扫描能明显提高脑转 移灶的检出率，应作为首选扫描序列。

Objective To discuss the clinical value of MRI contrast-enhancement scan in the evaluation of cerebral metastasis after radical mastectomy of breast cancer. Methods Clinical and MRI data of 32 patients with cerebral metastasis after radical mastectomy of breast cancer were retrospectively analyzed. All cases were Examinedwith conventional brain T1WI, T2WI plain scan, fluid attenuated inversion recovery (FLAIR) ,diffusion weighted imaging (DWI) scan and T1WI enhancement scan.To analyzed the display ability of all sequence in the metastatic lesions. Results 284 parenchyma lesions were distributed in the brain with all the scan sequence,whichmetastased in the brain parenchyma and meningeal . All the lesions showed heterogeneous hypointense or isointense on T1WI, hyperintense or isointense on T2WI, FLAIR and DWI with signal uniform or non-uniform, The solid masses were enhanced at different extension. The detection rate of the enhanced scanning to the metastasis was higher than other scanning sequences, The difference was statistically significant (P<0.05). Conclusion MRI multiple sequence scan were helpful for diagnosis and differential diagnosis of brain metastasis after radical mastectomy of breast cancer, Contrastenhanced scanning is the first choice because of whichcan significantly improve the detection rate of brain metastases.